My biggest tips for SEO in 2012.
1. Quality and Unique Content - Post panda, Google wants to see more quality, unique content. And that includes the content on your site as well as what is linking to you. If you want to get great results, write great content that is relevant to the search terms that you are targeting.
2. Diversify Links - As we have seen with all of the Google updates, you don't want to be in the place where an algorithm change is going to wipe out all of your traffic overnight. Make sure that you are getting links from a variety of places. That way, if Google devalues some, your others will carry you through.
3. Nail Your On Page SEO - Google is kind enough to give us a pretty good idea what they are looking for as far as on page optimization. Don't ignore this! Make sure that you are using your title tags, h1, h2, alt tags for images, and that you have an effective link structure.